Influência dos mananoligossacarídeos nos níveis séricos, hepáticos e renais de cálcio, fósforo, magnésio, cobre, selênio, zinco e ferro em ratos wistar

Abstract

This study aimed to determine the effect of including three different MOS (MOS) in Wistar rat diet in the growth phase, as an experimental model, measurement of blood, liver and kidney concentration of some mineral elements (Ca, P, Mg Cu, Se, Zn and Fe). Were used 160 rats with 23 days old, average of 46.17 ± 4.99 g body weight, fed for 56 days and distributed in a randomized block design with four groups: Control (GC), MOS 1 (GM1), MOS 2 (GM2) and MOS 3 (GM3) in four moments. Every 14 days the serum samples were collected, liver and kidney and analyzed with optical emission spectrometry inductively coupled plasma (ICP-OES). Mineral concentrations were used for the preparation of simple linear regression models using the time in days as independent variable. The regression coefficients and respective intercepts were compared between experimental groups, two by two, by the unpaired t test, with 5% significance. The MOS supplemented with different groups showed increased levels of all the minerals in serum and liver and kidney tissues compared to controls. Groups of animals supplemented with MOS differ significantly only in relation to the mineral calcium. These results suggest that dietary supplementation with different MOS can be beneficial for increasing the absorption of minerals Ca, P, Mg, Cu, Se, Zn, and Fe in rats as experimental models.