Aplicabilidade de uma película de celulose cristalina no tratamento de feridas cutâneas induzidas em ratos wistar

Abstract

Wound healing aims to restore the morphological and functional integrity of the skin. This study evaluates by means of clinical and histologic healing process of skin wounds induced experimentally in rats using a film crystalline cellulose Veloderm ®. Thirty-two rats were divided into two groups: control group (CG) wounds treated with a solution of sodium chloride 0.9% and group veloderm (GV) wounds treated with a film of crystalline cellulose and were evaluated for 26 days at different times. Weight loss was observed in animals from both groups in the early stages, and greater weight gain in the final moments of the GV to the animal, the temperature oscillations in the two groups with predominance in some moments of hypothermia, pinkish wound in the two groups across all time points, greater granulation tissue in animals of CG, the presence of little oozing from the wound and feature in GV and more serous exudation in characteristic bloody GC, GC in the presence of pain and pain in the absence of GV and greater contraction of the wound to the GC, but with complete healing in early GV. Thus, we conclude that the crystalline cellulose film Veloderm ® is effective in the treatment of skin wounds in rats, easy to apply and use, promotes protection and lessen the pain by bringing comfort to the patient, enhances visualization and control of the evolution of the injury keeping humidity, as well as a cost-effective.