Associação de bactérias probióticas potencializa a produção de anticorpos antirrábicos em bovinos vacinados contra raiva

Abstract

This study evaluated the effect of supplementation with a combination of probiotic microorganisms, added to a mineral mixture in different doses/day, in the production of serum antibodies against the rabies virus in primo vaccinated cattle. Forty-two male Nelore cattle, divided into three groups (n = 14): control group (CG) received 70 grams of mineral mixture/animal/day; probiotic groups 4 grams (G4P) and 8 grams (G8P) received 70 grams of mineral mixture/animal/day with 4 and 8 grams of added probiotics respectively. The individual anti-rabies antibody titers were determined using the technique of seroneutralization in cells based on the Rapid Fluorescent Focus Inhibition Test (RFFIT). The results obtained were compared using the unpaired t test with a 5% significance level. There were statistical differences in the mean serum concentrations between the CG, G4P and G8P groups, 30 and 60 days after the primo vaccination and after 60 days only the G8P group demonstrated minimum protective antibody titers in 100% of the animals. There is evidence of beneficial effects attributed to the association between probiotic microorganisms and the anti-rabies humoral immune response; in addition, an increase in the dose incorporated into the mineral mixture maintains high levels of serum antibodies in primo vaccinated cattle.