Hormônio do crescimento, associado ou não ao exercício resistido, na ciclicidade reprodutiva, endocrinologia e morfometria uterina de ratas wistar

Abstract

The aim of this study was to verify the use of growth hormone (GH), with or without resisted exercise, the estrous cycle, the dosage of the estradiol and progesterone and Wistar rats endometrium thickness. The rats were divided into four groups (n = 10): CT (Control); Ex (resisted exercise - water jumps with 50% of body weight); GH (0,2UI / kg administered GH); and ExGH (GH and Ex groups combined treatment). The estrous cycle phase of rats were determined by vaginal cytology, daily for 29 days. The rats plasma was used for hormone dosage and the endometrium thicknesses were evaluated by histology. We used the Shapiro-Wilk normality presupposition. For samples that was parametric, ANOVA was used with Tukey, for no parametric samples, Kruskal-Wallis with Student-Newman-Keuls test was used (p<0.05). There are a greater reproductive cycles number in CT than in other groups during the 29 days period (p>0.05), no difference were found between the hormones dosage groups neither endometrial thickness. Therefore, it is concluded that GH and resisted exercises both combined affect females reproductive cycle, they reduced the number of cycles of rats but they do not change the estradiol and progesterone concentrations, neither endometrial thickness.