Comparação entre o teste de meniscometria de tira e outros testes oftálmicos em cães com olhos normais e com ceratoconjuntivite seca

Abstract

The objective of the present study was correlate the strip meniscometry test (SMT) with the Schirmer tear test 1 (STT-1), the tear film break up test (TBUT), and the lissamine green test (LGT) in dogs with normal eyes and with dry keratoconjunctivitis (KCS). Were evaluated 138 eyes from 69 dogs, including 78 normal eyes and 60 eyes diagnosed with KCS. The tests were performed in the following sequence: the STT-1 was used to allocate the dogs to the normal group or the KCS group, followed by the SMT, TBUT, and LGT. The results in means and standard deviations for the normal group were: 23.68±4.25 (STT-1), 9.43±1.59 (SMT), and 23.06±6.95 (TBUT); LGT 7 positive eyes; and for the KCS group were: 6.20±4.45 (STT-1), 3.02±2.52 (SMT), and 11.62±4.53 (TBUT); LGT 14 positive eyes. There was a positive correlation between the SMT and the STT-1 and TBUT, as well as a negative correlation between the SMT and LGT. The correlation was very high between the SMT and STT-1 (r=0.87, p<0.001), moderate between the SMT and TBUT (r=0.61, p<0.001) and very low between the SMT and LGT (r=-0.17, p<0.001). The cut-off considered for the SMT was 7.5 mm/5 sec according to the ROC curve, presenting a sensitivity of 100% and specificity of 91.7%. This study provided SMT values in normal and KCS eyes for dogs, revealing high sensitivity and specificity compared with the STT-1 and a good predictive power for the diagnosis of KCS, showing that in the future, the SMT could replace the STT-1.